Course Details

ELE 451 Fundamentals of Biomedical Engineering
2021-2022 Spring term information

The course is not open this term

Timing data are obtained using weekly schedule program tables. To make sure whether the course is cancelled or time-shifted for a specific week one should consult the supervisor and/or follow the announcements.

Course definition tables are extracted from the ECTS Course Catalog web site of Hacettepe University ( in real-time and displayed here. Please check the appropriate page on the original site against any technical problems. Course data last updated on 26/05/2022.


Course Name Code Semester Theory
Credit ECTS
Prerequisite(s)ELE203 Circuit Theory I
Course languageEnglish
Course typeElective 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Question and Answer
Problem Solving
Instructor (s)Faculty members 
Course objectiveThe content of the lecture is designed for the objective of examining the terminology, the theory and the applications of interdisciplinary biomedical engineering field in introduction level, classifying electronic equipments in medical area and teaching their working principles. The generation of biosignals, their mathematical models, measurement techniques and requirements of medical equipments are composing the information that students gain under this course objective.  
Learning outcomes
  1. A student who completes the course successfully will apply the measurement and evaluation criteria to biomedical engineering field,
  2. Develop awareness for biomedical equipment design restrictions and safety issues,
  3. Learn the basic mechanism of bioelectrical signals and generation of action potentials, provide models for their behaviours,
  4. Classify the quantities that are measured in biomedical studies and associated sensors, compare their transduction functions,
  5. Learn to process and amplify bioelectrical signals,
  6. Learn the measures for protection of patients and devices,
  7. Have the knowledge of hardware related to some important recording systems and devices used in biomedical field.
Course Content1. Main principles in biomedical instrumentation, requirements and restrictions,
2. Bioelectric signals: excitible cells and membrane structures, ionic activities,
3. Action potentials and its firing mechanism: active cell model , propagation,
4. Displacement, force, pressure, temperature measurements and associated sensors ,
5. Biopotential electrodes.
6. Amplifying and processing bioelectric signals, instrumentation amplifiers, interference reduction, isolation,
7. ECG, EMG,EEG recording systems, hardware details, lead-electrode selections.
ReferencesJ.G. Webster, editör, Medical Instrumentation: Application and Design, Wiley, 2009.
J. Malmivuo, R. Plonsey, Bioelectromagnetism, Oxford University Press, 1995.
J. Enderle et al, Introduction to Biomedical Engineering, Academic Press, 2000.
Bronzino, J.D. editör, The Biomedical Engineering Handbook, IEEE Press,1995.
J.J. Carr, J.M. Brown, Introduction to Biomedical Equipment Technology,

Course outline weekly

Week 1Introduction, main principles in biomedical instrumentation,
Week 2Main principles in designing biomedical instrumentation, requirements, restrictions, engineering ethics and regulations in biomedical engineering
Week 3Excitible cells and membrane structures, ionic activities: Nernst Potentials,
Week 4Membrane structures, ionic activities: Goldman Equation,
Week 5Action potentials and its firing mechanism: active cell model , propagation,
Week 6Active cell model , propagation: Cable Equation, Voltage Clamp Experiment,
Week 7Displacement, force, pressure and associated sensors ,
Week 8Displacement, temperature measurements and associated sensors ,
Week 9Midterm examination
Week 10Biopotential electrodes,
Week 11Amplifying and processing bioelectric signals,
Week 12Instrumentation amplifiers, interference reduction, isolation amplifiers,
Week 13ECG recording systems, hardware details, lead-electrode selections.
Week 14EMG,EEG recording systems, hardware details, lead-electrode selections.
Week 15Preparation for Final exam
Week 16Final exam

Assesment methods

Course activitiesNumberPercentage
Field activities00
Specific practical training00
Final exam155
Percentage of semester activities contributing grade succes345
Percentage of final exam contributing grade succes155

Workload and ECTS calculation

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 3 42
Laboratory 0 0 0
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)13678
Presentation / Seminar Preparation000
Homework assignment2612
Midterms (Study duration)11010
Final Exam (Study duration) 11515
Total Workload3140157

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
1. PO1. Possesses the theoretical and practical knowledge required in Electrical and Electronics Engineering discipline.    X 
2. PO2. Utilizes his/her theoretical and practical knowledge in the fields of mathematics, science and electrical and electronics engineering towards finding engineering solutions.    X
3. PO3. Determines and defines a problem in electrical and electronics engineering, then models and solves it by applying the appropriate analytical or numerical methods.     X
4. PO4. Designs a system under realistic constraints using modern methods and tools.   X 
5. PO5. Designs and performs an experiment, analyzes and interprets the results.  X  
6. PO6. Possesses the necessary qualifications to carry out interdisciplinary work either individually or as a team member.   X  
7. PO7. Accesses information, performs literature search, uses databases and other knowledge sources, follows developments in science and technology.  X  
8. PO8. Performs project planning and time management, plans his/her career development. X   
9. PO9. Possesses an advanced level of expertise in computer hardware and software, is proficient in using information and communication technologies. X   
10. PO10. Is competent in oral or written communication; has advanced command of English.  X  
11. PO11. Has an awareness of his/her professional, ethical and social responsibilities.  X  
12. PO12. Has an awareness of the universal impacts and social consequences of engineering solutions and applications; is well-informed about modern-day problems.  X  
13. PO13. Is innovative and inquisitive; has a high level of professional self-esteem.  X  

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest

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